Module guide WS 2018-2022

Module LS4185 B

Module part LS4185B: Rational Drug Design (RatDruDes)


1 Semester
Turnus of offer:

each summer semester
Credit points:

Course of studies, specific field and terms:
  • Master Infection Biology 2018 (Module part of a compulsory module), Microbiology, 2nd semester
  • Master Infection Biology 2012 (Module part of a compulsory module), Microbiology, 2nd semester
Classes and lectures:
  • Rational Drug Design (lecture, 2 SWS)
  • 30 Hours in-classroom work
  • 60 Hours private studies
Contents of teaching:
  • Drug development – an overview
  • Target identification and validation
  • Role of x-ray crystallography in drug development
  • Structure-based drug design – Principles and methods
  • Case studies of structure-based drug development
  • Combinatorial approach for nucleic acid therapeutics identification
  • Oligomeric nucleic acid therapeutics
  • Cellular applications of nucleic acid therapeutics via non-viral carrier systems
  • Basic strategies of drug design
  • The path from the discovery of an active principle to a marketable product. Rational drug design
  • NMR and crystallography as fundamental tools for finding and optimizing active agents
  • Structure and effect relationships will be demonstrated using examples, techniques used for theoretical prediction and experimental proof will be introduced, especially the complementary approach using crystallographic methods and NMR experiments
  • Students will critically evaluate these methods and perceive their limits
Grading through:
  • see Notes
Responsible for this module:
  • Siehe Hauptmodul
  • Prof. Dr. rer. nat. Thomas Peters
  • Prof. Dr. rer. nat. Rolf Hilgenfeld
  • Dr.rer.nat Sonja Petkovic
  • Prof. Dr. rer. nat. Tobias Restle
  • Prof. Dr. Lars Redecke
  • -: Current scientific literature
  • offered only in English

Part of module LS4185-KP03.

The module part includes a written Test as the only form of examination.

The total amount of time allocated to a written examination is usually between 60 and 180 minutes (Examination Regulations).

Letzte Änderung: