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Module guide

Module LS4145-KP05

Infection Biology 2 (InfBiol2)

Duration:


1 Semester
Turnus of offer:


each summer semester
Credit points:


5
Course of studies, specific field and terms:
  • Master Infection Biology 2018 (compulsory), Infection Biology, 2nd semester
  • Master Infection Biology 2012 (compulsory), Infection Biology, 2nd semester
Classes and lectures:
  • Infection Biology 2 (practical course, 3 SWS)
  • Infection Biology 2 (lecture, 2 SWS)
Workload:
  • 75 Hours in-classroom work
  • 75 Hours private studies
Contents of teaching:
  • Cellular and molecular mechanisms of infections
  • Interaction of pathogens with cells of the innate and adaptive immune system, antimicrobial effector mechanisms
  • Extra- and intracellular pathogens, molecular mechanisms of intracellular survival
  • Host cell death and its consequences
  • Innate and adaptive immune functions and practical applications
  • Background and practical application of cell culture, virus cultivation, and virus quantification (Endpoint titration and plaque assay)
  • Aseptic techniques
  • Basic knowledge in genetic engineering and legislation, in Good Scientific Practis with regards to teh rules of the UzL.
  • Laboratory safety (GHS)
  • Basic laboratory calculations
Qualification-goals/Competencies:
  • The students have the scientific competency to implement their detailed knowledge of infectious agents, infectious diseases and their pathomechanisms, their detailed understanding of antimicrobial defense mechanisms at the cellular and molecular level.
  • They are competent in theory and in practical skills in laboratory techniques to approach infectious disease research projects in a successful manner with regards to teh rules of Good Scientific Practise of the UzL.
  • They know the principles of virus cultivation and titration and can apply this practically.
  • They know the principles of tissue culture and can apply this practically.
  • They can perform standard laboratory calculations and unit conversions.
  • They have the methodological competence, to use flow cytometric approaches addressing the host-pathogen interaction at single cell level (phagocytosis, cell activation, cell death, cytokine formation).
  • They can process and interpret data and can communicate it to peers
  • They have the communication competency to convey the underlying principles of techniques of infection research.
  • They understand laboratory safety procedures and can apply them practically
Grading through:
  • Oral examination
Is requisite for:
Requires:
Responsible for this module:
  • Prof. Dr. rer. nat. Stefan Taube
Teachers:
  • Prof. Dr. Ulrich Schaible
  • Prof. Ph.D. Tamás Laskay
  • Prof. Dr. Admar Verschoor
  • PD Dr. rer. nat. Norbert Reiling
  • Prof. Dr. rer. nat. Stefan Taube
  • Dr. math. et dis. nat. Jeroen Mesters
  • Dr. rer. nat. Tobias Dallenga
Literature:
  • S.J. Flint: Principles of Virology – Vol I and II - ASM Press, Washington DC
  • • Mims' Pathogenesis of Infectious Disease.: Academic Press. Ed. Nash, Dalziel, Fitzgerald
  • • 2014. “Murine Norovirus: Propagation, Quantification, and Genetic Manipulation.”: 33. Hoboken, NJ, USA: John Wiley & Sons, Inc.: 15K.2.1–K.2.61.
Language:
  • offered only in English
Notes:

Prerequisites for the module:
- LS4045-KP05 Diagnostical Methods in Microbiology and Pathology
- LS4015-KP06 Infection Biology 1
- Participation in the Biological Safety Instruction is mandatory

Prerequisites for admission to the written examination:
- Regular and successful attendance is strongly recommended in addition to independent study as solid preparation for the oral examination.

Module Exam(s):
- LS4145-L1 Infection Biology 2: The module will be graded by means of a 30-minute oral examination at the end of the practical, where students will present their own data. Both theoretical and practical knowledge will be assessed. 100% of the module grade.

If the oral examination is not passed succesfully, he/she will have to repeat the whole module one year later.

Letzte Änderung:
21.4.2021