Website
Module Guide before WS 2016/17

Modul MZ5110 A

Medical Cell Biology 1: Part A: Immunology (MZB1AImmu)

Duration:


1 Semester
Turnus of offer:


each winter semester
Credit points:


6
Course of studies, specific field and terms:
  • Master MLS 2009 (Module part of a compulsory module), neuroscience, 1st semester
Classes and lectures:
  • Immunology (seminar, 2 SWS)
  • Immunology (lecture, 2 SWS)
Workload:
  • 60 Hours in-classroom work
  • 120 Hours private studies
Contents of teaching:
  • Lecture: Introduction to immunology
  • Cells of the innate immune system
  • Innate immune system: pathogen recognition
  • Complement and inflammation
  • Introduction into the adaptive immune system
  • Antigen-presentation and T cell activation
  • Immunological memory
  • Immune system and infektion I: bacteria, worms, fungi
  • Immune system and infektion II: Viruses
  • Signal transduktion in immune cells
  • Organs and tissues of the immune system, homing
  • Immunpathogenesis I: allergy and asthma
  • Immunpathogenesis II: autoimmune diseases
  • Immunprivileged Organs
  • Hematopoiesis and hematopoietic stem cells
  • Experimental and clinically applied biologicals
  • Seminar: PCR
  • ELISA/ELISPOT
  • Flow cytometry I: FACS-Analysis
  • Flow cytometry II: MACS, FACS-Sort
  • Flow cytometry III: Practical course at the ISEF (MACS, Analysis, Sort)
  • Conventional and confocal microscopy
  • Methods in signal transduction
  • Migration: transwell assay; adhesion test etc.
  • 2-Photon microscopy
  • Animal models in life science
  • Genetically modified mice I: conventional transgenics and KO mice
  • Genetically modified mice II: conditional KO und Knock In Mice
Qualification-goals/Competencies:
  • Students are able to:
  • Name cells of the immune system and allocate their functions
  • Name organs that belong to the immune system and allocate their functions
  • Name mechanisms, cells and molecules of the innate and adaptive immune system and allocate their functions during bacterial, viral and fungal infections
  • Name and allocate functions of molecules important for B cell -T cell co-cooperation
  • Name and allocate the functions of molecules and antigen-presenting cells important for T cell activation and differentiation
  • Name molecules of the complement system and allocate their functions for immune protection and immune diseases
  • Name structure and function of the distinct antibody classes
  • Name and allocate functions of molecules important for homing and migration of immune cells
  • Name and allocate functions of molecules important for the initiation and resolution of inflammation
  • Name the functions of immunological memory
  • Name molecules and mechanisms involved in the development of B cell and T cell memory
  • Describe the principal sequence of an immune reaction during infection and after vaccination
  • Name genetic, molecular and cellular disturbances of the immune system relevant for immune deficiency, autoimmune and allergic diseases
  • Describe the basic mechanisms of signal transduction in immune cells
  • Name mechanisms and molecules involved in hematopoiesis
  • Name and explain immunological methods
  • Present and discuss scientific data
Grading through:
  • written exam
Responsible for this module:
  • Prof. Dr. rer. nat. Rudolf Manz
Teachers:
  • Prof. Dr. rer. nat. Rudolf Manz
  • Prof. Dr. med. Jörg Köhl
  • Prof. Dr. rer. nat. Marc Ehlers
Literature:
  • Janeway, Travers, Walport, Shlomchik: Immunologie - Spektrum Akademischer Verlag
  • : Original- und Übersichtsartikel
Language:
  • offered only in English
Notes:

(Part of the module MZ5110)

Letzte Änderung:
17.7.2019