Module Guide since WS 2016/17

Modul LS2300-KP08, LS2301

Biophysical Chemistry (BPCKP08)


1 Semester
Turnus of offer:

each summer semester
Credit points:

Course of studies, specific field and terms:
  • Master CLS 2023 (compulsory), MML with specialization in Life Science, 2nd semester
  • Bachelor MLS 2018 (compulsory), Chemistry, 4th semester
  • Bachelor MLS 2016 (compulsory), Chemistry, 4th semester
  • Master CLS 2016 (compulsory), MML with specialization in Life Science, 2nd semester
  • Bachelor Biophysics 2016 (compulsory), biophysics, 4th semester
  • Master CLS 2010 (optional subject), computational life science / life sciences, 2nd semester
  • Bachelor MLS 2009 (compulsory), life sciences, 4th semester
Classes and lectures:
  • Biophysical Chemistry (practical course, 3 SWS)
  • Biophysical Chemistry (exercise, 1 SWS)
  • Biophysical Chemistry (lecture, 3 SWS)
  • 80 Hours in-classroom work
  • 160 Hours private studies
Contents of teaching:
  • Lecture topics:
  • What is Biophysical Chemistry?
  • Basics of NMR spectroscopy
  • Basics of mass spectrometry
  • Theoretical calculation of molecules - Quantum mechanics or molecular mechanics?
  • Basics of chemical thermodynamics
  • Thermodynamics of ligand binding
  • Basics of chemical kinetics
  • Basics of enzyme kinetics
  • Molecular Mechanics
  • Practical works:
  • NMR, Molecular Modeling, experiments with a focus on thermodynamics and kinetics
  • Acquire basic knowledge on spectroscopic techniques to analyze (bio)molecules. Focus is on NMR and mass spectrometry techniques
  • Insight into properties (e.g. structure, dynamics, spectroscopic properties) of molecules employing theoretical models. Acquisition of basic knowledge to compute molecules
  • Application of laws of thermodynamics to describe chemical reactions and biological processes with a focus on binding and recognition reactions in biological systems
  • Acquire basic knowledge to analyze time courses of chemical reactions and biological processes
  • Acquisition of skills to work independently and self-determined in the laboratory with regard to the roles of GSP of the University of Lübeck and of the DFG-guidelines.
Grading through:
  • written exam
Responsible for this module:
  • Prof. Dr. rer. nat. Ulrich Günther
  • Prof. Dr. rer. nat. Ulrich Günther
  • PD Dr. phil. nat. Thomas Weimar
  • Peter Atkins and Julio de Paula: Physical Chemistry for the Life Sciences - Oxford, University Press, Freeman and Company, 2006, ISBN 0-1992-8095-9
  • Thomas Engel und Philip Reid: Physikalische Chemie - Pearson Studium, 2006, ISBN 13: 978-3-8273-7200-0
  • van Holde, Johnson & HoPrentice Hall: Principles of Physical Biochemistry - New Jersey, 1998, 2006, ISBN 0-13-720459-0
  • Atkins: Physical Chemistry - Oxford University Press, Oxford Mel-bourne Tokyo, 1998, ISBN 0-19-850101-3 Paperback, Deutsche Ausgabe (dritte Auflage) bei Wiley VCH, 2002: ISBN 3-527-30236-0 Wiley-VCH, Weinheim
  • Fersht, W. H.: Structure and Mechanism in Protein Science - New York, 1999, ISBN 0-7167-3268-8
  • Cantor & Schimmel: Biophysical Chemistry, Parts I-III - Freeman and Company, New York, 1980, ISBN 0-71671188-5 Paperback
  • H. Friebolin: Ein- und zweidimensionale NMR-Spektroskopie - Wiley-VCH
  • James Keeler and Peter Wothers: Chemical Structure and Reactivity: An integrated approach - Oxford University Press, 2008; second ed. 2013
  • offered only in German

Prerequisites for the modul:
- None

Prerequisites for admission to the written examination:
- Successful completion of the excercises as specified at the beginning of the semester

Modul exam(s):
- LS2300-L1: Biophysical Chemistry, written exam, 90 min, 100 % of module grade
- LS2300-L2: Practical course Biophysical Chemistry, ungraded practical course, 0 % of module grade, has to be passed

MML: Optional course in the 2nd semester master program with specialisation in Life Science

Biophysics: some specific practicals

The practical course takes place in September as compact course. Prerequisite LS1600 and LS2600

The module is better understandable if the modules Physics 1 or 2 have been attended before.

(Share of Institute of Physics in practical course is 25%.)

Letzte Änderung: