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Module Guide before WS 2016/17

Modul LS4130 A

Module part: Membrane Biophysics (Biophy2Mem)

Duration:


1 Semester
Turnus of offer:


each summer semester
Credit points:


4
Course of studies, specific field and terms:
  • Master MES 2020 (module part), mathematics / natural sciences, Arbitrary semester
  • Master Entrepreneurship in Digital Technologies 2020 (module part), Module part, Arbitrary semester
  • Master Entrepreneurship in Digital Technologies 2014 (module part), mathematics / natural sciences, Arbitrary semester
  • Master MES 2014 (module part), mathematics / natural sciences, Arbitrary semester
  • Master MLS 2009 (Module part of a compulsory module), structure biology, 2nd semester
Classes and lectures:
  • Basics of Membrane Biophysics (exercise, 1 SWS)
  • Basics of Membrane Biophysics (lecture, 2 SWS)
Workload:
  • 75 Hours private studies
  • 45 Hours in-classroom work
Contents of teaching:
  • Importance and function of cell membranes: structure, physical function and dynamic models
  • Basics of the membrane components
  • Thermodynamic self-assembling of lipids and reconstitution techniques
  • Transmembrane and intrinsic membrane potentials
  • Mechanical properties of lipid membranes
  • Physical basics of membrane transport mechanisms
  • Investigations using lipid monolayer
  • Electrical and optical experiments using planar lipid bilayers
  • Examples for interaction mechanisms between peptides/ proteins and planar membranes
  • Spectroscopic methods on membranes and membrane proteins
  • Light and force microscopy on membranes and membrane proteins
Qualification-goals/Competencies:
  • The students can explain the components and the structure of biological membranes.
  • They can explain the role and function of membrane lipids and proteins.
  • They can explain the mechanical and electrical properties of membranes.
  • They can explain the reconstitution of artificial lipid membranes.
  • They can explain the methods for the investigation of artificial and natural membranes.
  • They can explain the application of biophysical methods to biomedical questions, such as the characterization of membrane-active toxins.
Grading through:
  • written exam
Responsible for this module:
  • Siehe Hauptmodul
Teachers:
  • Prof. Dr. rer. nat. Thomas Gutsmann
  • Prof. Dr. rer. nat. Andra Schromm
  • Dr. Christian Nehls
Literature:
  • Adam, P. Läuger, G. Stark: Physikalische Chemie und Biophysik - Springer-Verlag, 4. Auflage 2003
  • W. Hanke, R. Hanke: Methoden der Membranphysiologie - Spektrum Akademischer Verlag, Auflage 1997
  • Ole G. Mouritsen: Life - As a Matter of Fat - Springer 2005, ISBN 987-3-540-23248-3
  • Thomas Heimburg: Thermal Biophysics of Membranes - Whiley-VCH 2007, ISBN 978-3-527-40471-1
  • Lukas K. Buehler: Cell Membranes - Garland Science 2016, ISBN 978-0-8153-4196-3
Language:
  • English, except in case of only German-speaking participants
Notes:

Prerequisites for attending the module:
- None

Prerequisites for the exam:
- None

Part of the module LS4130
One choise of two.

Letzte Änderung:
16.4.2021