Website
Module Guide before WS 2016/17

Modul LS5200 ZG

Module part: Progenitors (Progenitor)

Duration:


1 Semester
Turnus of offer:


each winter semester
Credit points:


3
Course of studies, specific field and terms:
  • Master MLS 2009 (Module part of a compulsory module), advanced curriculum MLS, 3rd semester
Classes and lectures:
  • Progenitor Cells (seminar / exercises, 2 SWS)
Workload:
  • 60 Hours private studies
  • 30 Hours in-classroom work
Contents of teaching:
  • Types of stem cells: (i) embryonic stem cells (ESC), (ii) fetal stem cells (FSC), (iii) adult stem cells (aSC), (iv) tumor stem cells (CSC), (v) induced pluripotent stem cells (iPS)
  • Definitions: stem cell/progenitor; features of neural (NSC), mesenchymal (MSC), hematopoietic (HSC) and tumor- (CSC) stem cells
  • Characteristics and generation of iPS
  • Characteristics of the stem cell niche
  • non-neural and neural differentiation
  • Neurogenesis: (i) neuro-epithelial cells, (ii) radial glia, (iii) types of neuronal and glial progenitors
  • Factors regulating differentiation; factor-cocktails for the induction & differentiation of iPS
Qualification-goals/Competencies:
  • They can explain the features of ESCs, FSCs, aSCs, CSCs and iPS
  • They can list the characteristics and significance of NSCs, MSCs, HSCs and CSCs
  • They can explain the production and significance of iPS
  • They can explain the structure of the stem cell niche and its regulatory role
  • They can detail protocols of directed differentiation (e.g. neural versus non-neural)
  • Using neurogenesis as an example, they can tell how stem cells differentiate and what the terms „cell fate decision“ and „lateral inhibition“ indicate
  • They can name factors which promote the stem cell character and which are used to allow the production of iPS cells or their differentiation, respectively
Grading through:
  • Oral presentation and exercise with written report
Responsible for this module:
  • Siehe Hauptmodul
Teachers:
  • PD Dr. rer. nat. Christina Zechel
Literature:
  • : Originalliteratur und Reviews zu den einzelnen Themenabschnitten
Language:
  • English, except in case of only German-speaking participants
Notes:

Only for MLS.
Prerequisites: Passed all modules of the 1. and 2. semester MSc

Letzte Änderung:
16.4.2021