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Module Guide since WS 2016/17

Modul LS3150-KP10

Molecular Biology (MolBioKP10)

Duration:


1 Semester
Turnus of offer:


each winter semester
Credit points:


10
Course of studies, specific field and terms:
  • Bachelor MLS 2018 (compulsory), life sciences, 5th semester
  • Bachelor Nutritional Medicine 2018 (compulsory), life sciences, 5th semester
  • Bachelor Nutritional Medicine 2016 (compulsory), life sciences, 5th semester
  • Bachelor MLS 2016 (compulsory), life sciences, 5th semester
Classes and lectures:
  • Molecular Biology (exercise, 1 SWS)
  • Molecular Biology (seminar, 2 SWS)
  • Practical Course Molecular Biology (practical course, 3 SWS)
  • Molecular Biology (lecture, 2 SWS)
Workload:
  • 180 Hours private studies
  • 120 Hours in-classroom work
Contents of teaching:
  • Lectures: Typically, 5 coherent blocks will be lectured.
  • Basics: genetic engineering and gene regulation
  • Growth and aging: molecular processes during ontogenetic differentiation, maintenance and loss of function during aging of cells and organisms
  • Nucleic-acids: molecular basis, polymorphism, RNA-regulation. Diagnostic and possible therapeutic aspects
  • Molecular biology of plants: molecular basis as well as economic and ecological aspects of transgenic plants and herbicide resistance
  • Gene-therapeutic approaches and recombinant vaccines
  • Exercises: Reading of scientific articles and oral presentation
  • Conceptual design of publications
  • English as lingua franca in science
  • Practical course (in groups of 2): Safe handling of DNA and RNA
  • Detection of gene expression at the level of mRNA, ligation and transformation of plasmid DNA
  • Procaryotic expression of protein and identification of isolated proteins
  • Design of PCR-primers; specialized PCR techniques and identification of PCR products by electrophoresis
Qualification-goals/Competencies:
  • Students are able to present basic steps of genetic engineering
  • They can explain basic mechanisms of gene expression
  • They are able to formulate basic mechanisms of RNA-regulated biological systems
  • They can present examples for the relationship between pathophysiological processes and their molecular basis
  • They are able to explain principles of gene therapy
  • They acquire the competence to handle english literature and to present it in a scientific oral presentation
  • lab course: They have skills in basic molecular-biological techniques
  • lab course: They have the basic knowledge of safety at work in molecular-biological labs
  • lab course: They know the basics of scientific documentation techniques and can work in a team
  • Basic skills to design and perform their own experiments
Grading through:
  • written exam
Responsible for this module:
  • Prof. Dr. rer. nat. Jürgen Rohwedel
Teachers:
  • Prof. Dr. rer. nat. Jürgen Rohwedel
  • Prof. Dr. rer. nat. Norbert Tautz
  • PD Dr. rer. nat. Christina Zechel
  • Dr. rer. nat. Rosel Kretschmer-Kazemi Far
  • Dr. rer. nat. Olaf Isken
  • Prof. Dr. rer. nat. Jeanette Erdmann
Literature:
  • Alberts et al.: Molecular Biology of Cells - Garland Science
  • Lodish et al.: Molecular Cell Biology - Freeman
  • Buchanan et al.: Biochemistry and Molecular Biology of Plants - Wiley Verlag
  • : Versuchsanleitungen
  • : Course script
Language:
  • offered only in German
Notes:

Modul LS2000D Biochemistry 1 or LS2510 Biochemistry 2 is prerequisite for the practical course Moelcular Biology.

Prerequisites for attending the module:
- None

Prerequisites for the exam:
- Successful completion of assignments during the semester.

Letzte Änderung:
9.12.2019